Internship for Scientific Exchange - Identification and validation of novel targets for glial cells in neurological diseases - RiSE (9 months)

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Internship for Scientific Exchange - Identification and validation of novel targets for glial cells in neurological diseases - RiSE (9 months)

At Roche, we believe it’s urgent to deliver medical solutions right now - even as we develop innovations for the future. We are passionate about transforming patients’ lives and we are fearless in both decision and action. And we believe that good business means a better world.

That is why we come to work every single day. We commit ourselves to scientific rigour, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.

The Position

The RiSE program (Roche Internships for Scientific Exchange) is a highly competitive student research program at Roche. It offers the most talented postgraduate PhD and medical degree students the opportunity to be fully integrated into our interdisciplinary and international industry R&D environment. As a RiSE student you will enhance your competencies, gain valuable work experience with us, and eventually become part of a world-wide network of RiSE Alumni.

The Neuroscience and Rare Diseases Discovery and Translational Area (NRD DTA) is developing medicines for a range of serious neurological diseases, including multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, autism, spinal muscular atrophy, and Huntington’s disease.

As RiSE student in the NRD DTA you will join a cross-functional team from the Imaging group in Biomarkers and Translational Technologies (BTT), the Neuroimmunology section, and Biomarkers, Bioinformatics and Omics in Pharmaceutical Sciences (PS-BiOmics). You will work at the Roche Innovation Center Basel, Switzerland, and perform research in the discovery and validation of novel targets supporting the in vivo characterization of glial cells in a spectrum of neurological diseases. You will be hosted and mentored by Roche scientists who will guide you through your research and provide you with the needed work infrastructure and collaborative network.

During the internship your tasks will include

  • to mine existing gene and protein expression data sets for specific markers for glial cells.
  • to select the most promising targets based on their expression profile and suggested concentration in the CNS.
  • to identify and validate available antibodies for these targets and evaluate tissue expression on post mortem brain tissue (human disease and preclinical models) by immunoassays (WB, IHC, IF, ELISA).
  • to collaborate with expert departments on radioligand discovery and development and perform comparative in vitro/ex vivo autoradiography for selected targets with pre-existing radioligands.

Who You Are

You’re someone who wants to influence your own development. You’re looking for a company where you have the opportunity to pursue your interests across functions and geographies. Where a job title is not considered the final definition of who you are, but the starting point.

Moreover you are/have

  • Enrolled in a PhD or medical degree program at a university and are looking to expand your experience with an industry internship (must still be enrolled at university for 50% of the duration of the stay at Roche)
  • Profound knowledge in neuroscience/neuroimmunology is required. Experience in protein expression profiling and data analysis is considered a plus.
  • Experience with tissue processing and immunoassays.
  • An independent and proactive working style.

The preferred start date of the internship is September 2021 or upon availability.

Applications need to include a CV and a cover letter, as well as a letter from your academic supervisor supporting your application to the RiSE Program. Please note that due to regulations non-EU/EFTA citizens have to provide a certificate from the university stating that an industry internship is mandatory as part of the university training.

Do you know what Roche stands for? Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

If you still have questions, then please check our FAQs and videos on careers.roche.ch/faq

Tags: ROiQQ ROiLS ROiNSC RiSE

Wer wir sind

At Roche, 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche is an equal opportunity employer.

Job-Fakten

  • StandortSwitzerland,Basel-City,Basel
  • Funktion Vocational & Development Programs
  • Subfunktion Internship
  • Arbeitszeit Full time
  • Funktionsebene Entry Level
  • Art der Anstellung Temporary (Fixed Term)
  • Firma/ Division Roche Pharmaceuticals
  • Posted since 2021/04/22
  • Job-ID 202101-101282

Kontaktieren Sie uns

Mrs. Tina Hölzing

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Published on 2021-06-01. Original Job Ad