Internship Preformulation and Prediction Tools for Formulation Development in pCMC (Start 2022 for 6 months) Neu

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Internship Preformulation and Prediction Tools for Formulation Development in pCMC (Start 2022 for 6 months)

At Roche, we believe it’s urgent to deliver medical solutions right now - even as we develop innovations for the future. We are passionate about transforming patients’ lives. We are courageous in both decision and action. And we believe that good business means a better world.

That is why we come to work each day. We commit ourselves to scientific rigour, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.

Preclinical Chemistry, Manufacturing and Controls (pCMC) is a global function within Pharma Research and Early Development (pRED). We develop robust and innovative API synthesis and formulations to supply and enable key preclinical activities paving the way towards Entry Into Human. We are CMC experts and together with our discovery functions partners, we generate scientific and technical knowledge to assess the developability of drug candidates. We build our strength on a broad diversity of enthusiastic technical experts, pharmacists, chemists and analytical scientists delivering and innovating in the space of small molecules, peptides and oligonucleotides.

We are offering a 6 months internship in 2022 on the topic

Prediction tools for formulation development:

Utilizing computational pharmaceutics to perform in silico predictions of solubility enhancement in different formulation vehicles is key to the future of drug product development.

To develop computational tools that can streamline the development process, high quality datasets for drug compounds are pivotal. The project offers:

  • Measurement of drug solubility in excipient solutions using miniaturized 96-well based methods
  • Method development and drug quantification by UPLC
  • Solid state drug characterization by light microscopy, TGA, DSC, and XRPD methods
  • Calculation and evaluation of QSPR and quantum chemical properties

  • Development of prediction tools by applying different algorithms to the generated data.

Who you are:

You are preferably a postgraduate student (master or 2nd state examination) in the field of Pharmaceutical Sciences, Chemistry, Bio- or Physicalchemistry or Biotechnology with a strong interest in technical and analytical questions and Computational Pharmaceutics. Furthermore, you are interested in using and sharing your knowledge as part of your Internship in a modern working environment. Your further profile for this position:

  • Reliable and accurate working style
  • Team-oriented and decision-making personality
  • Self-sufficient, problem solving-oriented work habits
  • Good knowledge of MS-Office (Word, Excel, PowerPoint); experience in computational pharmaceutics/sciences and data analytics is a plus
  • Proficient in English, German is a plus

Your complete application includes the following documents:

  • A Current CV and a Motivation Letter
  • A certificate of enrollment (if you are currently studying).
  • For Non-EU/EFTA citizens: Due to regulations, you must provide a certificate issued by your university stating that an Internship is mandatory for your studies

Application Process:

Application deadline is November 15th, 2021

The Internship will start in 2022 for 6 months and could start between March 1st and June 1st, please indicate your preferred start in your application.

Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

Are you ready to apply? We are looking for someone who thinks beyond the job offered - someone who knows that this position can be a rare springboard to many other opportunities at Roche. When applying for this position, already project yourself in the future. Think about what could come next and how you would like to build your future.

Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

If you still have questions then please check our FAQs and videos oncareers.roche.ch/faq

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Wer wir sind

At Roche, 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche is an equal opportunity employer.

Job-Fakten

  • StandortSwitzerland,Basel-City,Basel
  • Funktion Vocational & Development Programs
  • Subfunktion Internship
  • Arbeitszeit Full time
  • Funktionsebene Entry Level
  • Art der Anstellung Temporary (Fixed Term)
  • Firma/ Division Roche Pharmaceuticals
  • Posted since 2021/10/06
  • Job-ID 202109-127214

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Am 16.10.2021 veröffentlicht. Originalanzeige